| Team Name | Round | Pick | Overall | Player Name | Position | NFL Team |
| The Dude is back | 1 | 1 | 1 | Breece Hall | RB | NYJ |
| DMB | 1 | 2 | 2 | Kenneth Walker | RB | SEA |
| Lites Out | 1 | 3 | 3 | Garrett Wilson | WR | NYJ |
| Zach | 1 | 4 | 4 | Drake London | WR | ATL |
| DMB | 1 | 5 | 5 | James Cook | RB | BUF |
| The Dude is back | 1 | 6 | 6 | Treylon Burks | WR | TEN |
| Lites Out | 1 | 7 | 7 | Jameson Williams | WR | DET |
| Lites Out | 1 | 8 | 8 | Chris Olave | WR | NO |
| Lites Out | 1 | 9 | 9 | Skyy Moore | WR | KC |
| Pedigree | 1 | 10 | 10 | Isaiah Spiller | RB | LAC |
| Lites Out | 1 | 11 | 11 | Christian Watson | WR | GB |
| WOLVERINES | 1 | 12 | 12 | Alec Pierce | WR | IND |
| Pedigree | 2 | 1 | 13 | Rachaad White | RB | TB |
| DMB | 2 | 2 | 14 | George Pickens | WR | PIT |
| Jobig | 2 | 3 | 15 | Tyrion Davis-Price | RB | SF |
| Zach | 2 | 4 | 16 | Dameon Pierce | RB | HOU |
| Lites Out | 2 | 5 | 17 | Zamir White | RB | LV |
| Hittem With The Hein | 2 | 6 | 18 | Brian Robinson | RB | WAS |
| Lites Out | 2 | 7 | 19 | Tyler Allgeier | RB | ATL |
| DMB | 2 | 8 | 20 | Jahan Dotson | WR | WAS |
| Night Owls F2 | 2 | 9 | 21 | David Bell | WR | CLE |
| Pedigree | 2 | 10 | 22 | Trey McBride | TE | ARI |
| Lites Out | 2 | 11 | 23 | Jerome Ford | RB | CLE |
| WOLVERINES | 2 | 12 | 24 | Russell Gage | WR | TB |
| Ohio Players | 3 | 1 | 25 | Brevin Jordan | TE | HOU |
| Lites Out | 3 | 2 | 26 | Pierre Strong | RB | NE |
| Ohio Players | 3 | 3 | 27 | John Metchie | WR | HOU |
| Zach | 3 | 4 | 28 | Kenneth Gainwell | RB | PHI |
| Zach | 3 | 5 | 29 | Mecole Hardman | WR | KC |
| Hittem With The Hein | 3 | 6 | 30 | DeVante Parker | WR | NE |
| Lites Out | 3 | 7 | 31 | Kyren Williams | RB | LAR |
| Casey's Golden Boys $77 (#227)** | 3 | 8 | 32 | Tom Brady | QB | TB |
| Night Owls F2 | 3 | 9 | 33 | Calvin Ridley | WR | ATL |
| Zach | 3 | 10 | 34 | Justyn Ross | WR | KC |
| Steel Curtain #227/$77 | 3 | 11 | 35 | Keaontay Ingram | RB | ARI |
| WOLVERINES | 3 | 12 | 36 | K.J. Osborn | WR | MIN |
| Ohio Players | 4 | 1 | 37 | Zach Wilson | QB | NYJ |
| DMB | 4 | 2 | 38 | Hassan Haskins | RB | TEN |
| The Dude is back | 4 | 3 | 39 | Jalen Tolbert | WR | DAL |
| Zach | 4 | 4 | 40 | Marlon Mack | RB | HOU |
| Jobig | 4 | 5 | 41 | D'Ernest Johnson | RB | CLE |
| Hittem With The Hein | 4 | 6 | 42 | J.D. McKissic | RB | WAS |
| Lites Out | 4 | 7 | 43 | Greg Dulcich | TE | DEN |
| Casey's Golden Boys $77 (#227)** | 4 | 8 | 44 | Jamison Crowder | WR | BUF |
| Night Owls F2 | 4 | 9 | 45 | Malik Willis | QB | TEN |
| Pedigree | 4 | 10 | 46 | Mac Jones | QB | NE |
| Steel Curtain #227/$77 | 4 | 11 | 47 | Wan'Dale Robinson | WR | NYG |
| Jobig | 4 | 12 | 48 | Laviska Shenault | WR | JAC |
| Ohio Players | 5 | 1 | 49 | Hayden Hurst | TE | CIN |
| DMB | 5 | 2 | 50 | Khalil Shakir | WR | BUF |
| Steel Curtain #227/$77 | 5 | 3 | 51 | Romeo Doubs | WR | GB |
| Zach | 5 | 4 | 52 | Isaih Pacheco | RB | KC |
| Jobig | 5 | 5 | 53 | Abram Smith | RB | NO |
| Hittem With The Hein | 5 | 6 | 54 | Jamaal Williams | RB | DET |
| Lites Out | 5 | 7 | 55 | Ty Chandler | RB | MIN |
| Casey's Golden Boys $77 (#227)** | 5 | 8 | 56 | Jelani Woods | TE | IND |
| Night Owls F2 | 5 | 9 | 57 | Kevin Harris | RB | NE |
| Pedigree | 5 | 10 | 58 | Kenny Pickett | QB | PIT |
| Steel Curtain #227/$77 | 5 | 11 | 59 | Tyquan Thornton | WR | NE |
| DMB | 5 | 12 | 60 | Calvin Austin | WR | PIT |
| Ohio Players | 6 | 1 | 61 | BAL Team Defense | DF | BAL |
| DMB | 6 | 2 | 62 | Gerald Everett | TE | LAC |
| Steel Curtain #227/$77 | 6 | 3 | 63 | Austin Hooper | TE | TEN |
| Zach | 6 | 4 | 64 | Desmond Ridder | QB | ATL |
| Jobig | 6 | 5 | 65 | Kennedy Brooks | RB | PHI |
| Hittem With The Hein | 6 | 6 | 66 | Sterling Shepard | WR | NYG |
| Lites Out | 6 | 7 | 67 | Snoop Conner | RB | JAC |
| Casey's Golden Boys $77 (#227)** | 6 | 8 | 68 | Daniel Jones | QB | NYG |
| Night Owls F2 | 6 | 9 | 69 | Marvin Jones | WR | JAC |
| Pedigree | 6 | 10 | 70 | Velus Jones | WR | CHI |
| Steel Curtain #227/$77 | 6 | 11 | 71 | Tyler Badie | RB | BAL |
| WOLVERINES | 6 | 12 | 72 | Harrison Bryant | TE | CLE |
| Ohio Players | 7 | 1 | 73 | Matt Prater | PK | ARI |
| Pedigree | 7 | 2 | 74 | Ryan Tannehill | QB | TEN |
| The Dude is back | 7 | 3 | 75 | Foster Moreau | TE | LV |
| Zach | 7 | 4 | 76 | IND Team Defense | DF | IND |
| Jobig | 7 | 5 | 77 | Isaiah McKenzie | WR | BUF |
| Hittem With The Hein | 7 | 6 | 78 | Darrel Williams | RB | KC |
| Lites Out | 7 | 7 | 79 | Cade York | PK | CLE |
| Casey's Golden Boys $77 (#227)** | 7 | 8 | 80 | Matt Breida | RB | NYG |
| Night Owls F2 | 7 | 9 | 81 | Jameis Winston | QB | NO |
| The Dude is back | 7 | 10 | 82 | Ke'Shawn Vaughn | RB | TB |
| Steel Curtain #227/$77 | 7 | 11 | 83 | Jared Goff | QB | DET |
| WOLVERINES | 7 | 12 | 84 | GB Team Defense | DF | GB |
