| Team Name | Round | Pick | Overall | Player Name | Position | NFL Team |
| Double Doink | 1 | 1 | 1 | Breece Hall | RB | NYJ |
| Double Doink | 1 | 2 | 2 | Kenneth Walker | RB | SEA |
| Castle Crue V | 1 | 3 | 3 | Drake London | WR | ATL |
| Scumpuppies of the North | 1 | 4 | 4 | Treylon Burks | WR | TEN |
| vcstaff | 1 | 5 | 5 | Garrett Wilson | WR | NYJ |
| Hillsdale Golden Tanks | 1 | 6 | 6 | Jameson Williams | WR | DET |
| Hillsdale Golden Tanks | 1 | 7 | 7 | Chris Olave | WR | NO |
| Castle Crue V | 1 | 8 | 8 | James Cook | RB | BUF |
| Scumpuppies of the North | 1 | 9 | 9 | Skyy Moore | WR | KC |
| The Experiment | 1 | 10 | 10 | Christian Watson | WR | GB |
| Scumpuppies of the North | 1 | 11 | 11 | Rachaad White | RB | TB |
| GREMMINGER | 1 | 12 | 12 | George Pickens | WR | PIT |
| Double Doink | 2 | 1 | 13 | Jahan Dotson | WR | WAS |
| vcstaff | 2 | 2 | 14 | Albert Okwuegbunam | TE | DEN |
| Castle Crue V | 2 | 3 | 15 | Dameon Pierce | RB | HOU |
| Scumpuppies of the North | 2 | 4 | 16 | John Metchie | WR | HOU |
| Brooklyn Beach Chickens | 2 | 5 | 17 | David Njoku | TE | CLE |
| GREMMINGER | 2 | 6 | 18 | Trey McBride | TE | ARI |
| Hillsdale Golden Tanks | 2 | 7 | 19 | Isaiah Spiller | RB | LAC |
| VROSE IO Dyno 500 1 | 2 | 8 | 20 | David Bell | WR | CLE |
| HiFlyin MFs | 2 | 9 | 21 | Jalen Tolbert | WR | DAL |
| VROSE IO Dyno 500 1 | 2 | 10 | 22 | Zamir White | RB | LV |
| The Experiment | 2 | 11 | 23 | Tyler Allgeier | RB | ATL |
| GREMMINGER | 2 | 12 | 24 | Tyrion Davis-Price | RB | SF |
| Hillsdale Golden Tanks | 3 | 1 | 25 | Brian Robinson | RB | WAS |
| Sweet Pappy Johnson | 3 | 2 | 26 | Alec Pierce | WR | IND |
| Brooklyn Beach Chickens | 3 | 3 | 27 | Marlon Mack | RB | HOU |
| VROSE IO Dyno 500 1 | 3 | 4 | 28 | Greg Dulcich | TE | DEN |
| Sunrise Hangover | 3 | 5 | 29 | Wan'Dale Robinson | WR | NYG |
| HiFlyin MFs | 3 | 6 | 30 | Raheem Mostert | RB | MIA |
| HiFlyin MFs | 3 | 7 | 31 | Jelani Woods | TE | IND |
| The Experiment | 3 | 8 | 32 | Keaontay Ingram | RB | ARI |
| Hillsdale Golden Tanks | 3 | 9 | 33 | Khalil Shakir | WR | BUF |
| The Experiment | 3 | 10 | 34 | Kyren Williams | RB | LAR |
| The Experiment | 3 | 11 | 35 | Hassan Haskins | RB | TEN |
| VROSE IO Dyno 500 1 | 3 | 12 | 36 | Jamaal Williams | RB | DET |
| The Experiment | 4 | 1 | 37 | Romeo Doubs | WR | GB |
| Sweet Pappy Johnson | 4 | 2 | 38 | Jerome Ford | RB | CLE |
| Scumpuppies of the North | 4 | 3 | 39 | Justyn Ross | WR | KC |
| Scumpuppies of the North | 4 | 4 | 40 | Pierre Strong | RB | NE |
| Scumpuppies of the North | 4 | 5 | 41 | Jameis Winston | QB | NO |
| The Experiment | 4 | 6 | 42 | Malik Willis | QB | TEN |
| Hillsdale Golden Tanks | 4 | 7 | 43 | K.J. Osborn | WR | MIN |
| VROSE IO Dyno 500 1 | 4 | 8 | 44 | MIA Team Defense | DF | MIA |
| HiFlyin MFs | 4 | 9 | 45 | Kenny Pickett | QB | PIT |
| vcstaff | 4 | 10 | 46 | Isaih Pacheco | RB | KC |
| Sweet Pappy Johnson | 4 | 11 | 47 | Tyquan Thornton | WR | NE |
| The Experiment | 4 | 12 | 48 | Abram Smith | RB | NO |
| Double Doink | 5 | 1 | 49 | Hayden Hurst | TE | CIN |
| Sweet Pappy Johnson | 5 | 2 | 50 | Cade Otton | TE | TB |
| Castle Crue V | 5 | 3 | 51 | Calvin Austin | WR | PIT |
| Brooklyn Beach Chickens | 5 | 4 | 52 | Austin Hooper | TE | TEN |
| Brooklyn Beach Chickens | 5 | 5 | 53 | Velus Jones | WR | CHI |
| Brooklyn Beach Chickens | 5 | 6 | 54 | D'Onta Foreman | RB | CAR |
| Hillsdale Golden Tanks | 5 | 7 | 55 | D'Ernest Johnson | RB | CLE |
| VROSE IO Dyno 500 1 | 5 | 8 | 56 | O.J. Howard | TE | BUF |
| HiFlyin MFs | 5 | 9 | 57 | DeVante Parker | WR | NE |
| Brooklyn Beach Chickens | 5 | 10 | 58 | Sterling Shepard | WR | NYG |
| Brooklyn Beach Chickens | 5 | 11 | 59 | Tyler Badie | RB | BAL |
| The Experiment | 5 | 12 | 60 | KJ Hamler | WR | DEN |
| The Experiment | 6 | 1 | 61 | Van Jefferson | WR | LAR |
| Sweet Pappy Johnson | 6 | 2 | 62 | Robbie Anderson | WR | CAR |
| Castle Crue V | 6 | 3 | 63 | Eno Benjamin | RB | ARI |
| The Experiment | 6 | 4 | 64 | Samaje Perine | RB | CIN |
| Brooklyn Beach Chickens | 6 | 5 | 65 | Sammy Watkins | WR | GB |
| Double Doink | 6 | 6 | 66 | Cameron Brate | TE | TB |
| Hillsdale Golden Tanks | 6 | 7 | 67 | Cade York | PK | CLE |
| VROSE IO Dyno 500 1 | 6 | 8 | 68 | Jamison Crowder | WR | BUF |
| HiFlyin MFs | 6 | 9 | 69 | Mo Alie-Cox | TE | IND |
| Sunrise Hangover | 6 | 10 | 70 | Kevin Harris | RB | NE |
| The Experiment | 6 | 11 | 71 | Raleigh Webb | WR | BAL |
| Sunrise Hangover | 6 | 12 | 72 | Snoop Conner | RB | JAC |
| Double Doink | 7 | 1 | 73 | Damien Williams | RB | ATL |
| Sweet Pappy Johnson | 7 | 2 | 74 | Derrius Guice | RB | FA |
| Castle Crue V | 7 | 3 | 75 | Taysom Hill | TE | NO |
| Brooklyn Beach Chickens | 7 | 4 | 76 | Kenyan Drake | RB | LV |
| VROSE IO Dyno 500 1 | 7 | 5 | 77 | Chuba Hubbard | RB | CAR |
| Brooklyn Beach Chickens | 7 | 6 | 78 | Darrel Williams | RB | KC |
| Hillsdale Golden Tanks | 7 | 7 | 79 | Harrison Bryant | TE | CLE |
| VROSE IO Dyno 500 1 | 7 | 8 | 80 | Matt Prater | PK | ARI |
| HiFlyin MFs | 7 | 9 | 81 | Matt Ryan | QB | IND |
| vcstaff | 7 | 10 | 82 | Foster Moreau | TE | LV |
| Castle Crue V | 7 | 11 | 83 | IND Team Defense | DF | IND |
| Sunrise Hangover | 7 | 12 | 84 | Ricky Seals-Jones | TE | NYG |
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