| Team Name | Round | Pick | Overall | Player Name | Position | NFL Team |
| Hank | 1 | 1 | 1 | Breece Hall | RB | NYJ |
| Hank | 1 | 2 | 2 | Treylon Burks | WR | TEN |
| Depot | 1 | 3 | 3 | Kenneth Walker | RB | SEA |
| Night Owls SF BB F77 | 1 | 4 | 4 | Drake London | WR | ATL |
| Hank | 1 | 5 | 5 | Garrett Wilson | WR | NYJ |
| DSS SF BB #129 | 1 | 6 | 6 | Tom Brady | QB | TB |
| Depot | 1 | 7 | 7 | Jameson Williams | WR | DET |
| Show Me Your TDs | 1 | 8 | 8 | Kenny Pickett | QB | PIT |
| Depot | 1 | 9 | 9 | Skyy Moore | WR | KC |
| Mad Genius of FB 77SFBBD129 | 1 | 10 | 10 | Chris Olave | WR | NO |
| Hank | 1 | 11 | 11 | Christian Watson | WR | GB |
| Hank | 1 | 12 | 12 | George Pickens | WR | PIT |
| Don't Sleep on the Streets | 2 | 1 | 13 | Jahan Dotson | WR | WAS |
| Don't Sleep on the Streets | 2 | 2 | 14 | James Cook | RB | BUF |
| Don't Sleep on the Streets | 2 | 3 | 15 | Albert Okwuegbunam | TE | DEN |
| Night Owls SF BB F77 | 2 | 4 | 16 | Malik Willis | QB | TEN |
| Doubleteams U | 2 | 5 | 17 | Zamir White | RB | LV |
| DSS SF BB #129 | 2 | 6 | 18 | Tyler Allgeier | RB | ATL |
| Doubleteams U | 2 | 7 | 19 | Matt Corral | QB | CAR |
| Show Me Your TDs | 2 | 8 | 20 | Isaiah Spiller | RB | LAC |
| DSS SF BB #129 | 2 | 9 | 21 | Trey McBride | TE | ARI |
| Mad Genius of FB 77SFBBD129 | 2 | 10 | 22 | Rachaad White | RB | TB |
| Hank | 2 | 11 | 23 | David Bell | WR | CLE |
| Doubleteams U | 2 | 12 | 24 | Marlon Mack | RB | HOU |
| Doubleteams U | 3 | 1 | 25 | Corey Davis | WR | NYJ |
| Doubleteams U | 3 | 2 | 26 | Justyn Ross | WR | KC |
| Don't Sleep on the Streets | 3 | 3 | 27 | Desmond Ridder | QB | ATL |
| Tweety Birds | 3 | 4 | 28 | Dameon Pierce | RB | HOU |
| Depot | 3 | 5 | 29 | Khalil Herbert | RB | CHI |
| DSS SF BB #129 | 3 | 6 | 30 | David Njoku | TE | CLE |
| Tweety Birds | 3 | 7 | 31 | Sam Howell | QB | WAS |
| Show Me Your TDs | 3 | 8 | 32 | Gus Edwards | RB | BAL |
| Tweety Birds | 3 | 9 | 33 | John Metchie | WR | HOU |
| Mad Genius of FB 77SFBBD129 | 3 | 10 | 34 | Brian Robinson | RB | WAS |
| DSS SF BB #129 | 3 | 11 | 35 | Alec Pierce | WR | IND |
| Tweety Birds | 3 | 12 | 36 | Pierre Strong | RB | NE |
| Tweety Birds | 4 | 1 | 37 | Marquez Valdes-Scantling | WR | KC |
| Hank | 4 | 2 | 38 | Wan'Dale Robinson | WR | NYG |
| Don't Sleep on the Streets | 4 | 3 | 39 | Jalen Tolbert | WR | DAL |
| Night Owls SF BB F77 | 4 | 4 | 40 | Jerome Ford | RB | CLE |
| Depot | 4 | 5 | 41 | Eno Benjamin | RB | ARI |
| DSS SF BB #129 | 4 | 6 | 42 | DeVante Parker | WR | NE |
| Inglourious Basterds | 4 | 7 | 43 | Robert Tonyan | TE | GB |
| Show Me Your TDs | 4 | 8 | 44 | J.D. McKissic | RB | WAS |
| Tweety Birds | 4 | 9 | 45 | Damien Williams | RB | ATL |
| Mad Genius of FB 77SFBBD129 | 4 | 10 | 46 | Harrison Butker | PK | KC |
| Mahomes Golden Tanks | 4 | 11 | 47 | Joshua Palmer | WR | LAC |
| Hank | 4 | 12 | 48 | Jelani Woods | TE | IND |
| Doubleteams U | 5 | 1 | 49 | Matt Gay | PK | LAR |
| Mahomes Golden Tanks | 5 | 2 | 50 | Jimmy Garoppolo | QB | SF |
| Don't Sleep on the Streets | 5 | 3 | 51 | Tyquan Thornton | WR | NE |
| Night Owls SF BB F77 | 5 | 4 | 52 | Chuba Hubbard | RB | CAR |
| Depot | 5 | 5 | 53 | Keaontay Ingram | RB | ARI |
| Sno ball || | 5 | 6 | 54 | Jeremy Ruckert | TE | NYJ |
| Inglourious Basterds | 5 | 7 | 55 | Tyrion Davis-Price | RB | SF |
| Show Me Your TDs | 5 | 8 | 56 | DEN Team Defense | DF | DEN |
| Tweety Birds | 5 | 9 | 57 | BAL Team Defense | DF | BAL |
| Mad Genius of FB 77SFBBD129 | 5 | 10 | 58 | D'Onta Foreman | RB | CAR |
| Mahomes Golden Tanks | 5 | 11 | 59 | D'Ernest Johnson | RB | CLE |
| Doubleteams U | 5 | 12 | 60 | Samaje Perine | RB | CIN |
| Doubleteams U | 6 | 1 | 61 | Terrace Marshall | WR | CAR |
| Doubleteams U | 6 | 2 | 62 | Tim Patrick | WR | DEN |
| Don't Sleep on the Streets | 6 | 3 | 63 | Greg Dulcich | TE | DEN |
| Night Owls SF BB F77 | 6 | 4 | 64 | Kevin Harris | RB | NE |
| Depot | 6 | 5 | 65 | Ihmir Smith-Marsette | WR | MIN |
| DSS SF BB #129 | 6 | 6 | 66 | LAC Team Defense | DF | LAC |
| Inglourious Basterds | 6 | 7 | 67 | Nyheim Hines | RB | IND |
| Show Me Your TDs | 6 | 8 | 68 | Curtis Samuel | WR | WAS |
| Tweety Birds | 6 | 9 | 69 | Kyren Williams | RB | LAR |
| Mad Genius of FB 77SFBBD129 | 6 | 10 | 70 | GB Team Defense | DF | GB |
| Mahomes Golden Tanks | 6 | 11 | 71 | Sony Michel | RB | MIA |
| Doubleteams U | 6 | 12 | 72 | Brandon McManus | PK | DEN |
| Doubleteams U | 7 | 1 | 73 | Tyler Huntley | QB | BAL |
| Hank | 7 | 2 | 74 | Khalil Shakir | WR | BUF |
| Don't Sleep on the Streets | 7 | 3 | 75 | Romeo Doubs | WR | GB |
| Night Owls SF BB F77 | 7 | 4 | 76 | Younghoe Koo | PK | ATL |
| Depot | 7 | 5 | 77 | Jonnu Smith | TE | NE |
| DSS SF BB #129 | 7 | 6 | 78 | Dustin Hopkins | PK | LAC |
| Inglourious Basterds | 7 | 7 | 79 | Ryan Succop | PK | TB |
| Show Me Your TDs | 7 | 8 | 80 | Myles Gaskin | RB | MIA |
| Tweety Birds | 7 | 9 | 81 | Wil Lutz | PK | NO |
| Mad Genius of FB 77SFBBD129 | 7 | 10 | 82 | Isaiah McKenzie | WR | BUF |
| Mahomes Golden Tanks | 7 | 11 | 83 | Harrison Bryant | TE | CLE |
| Doubleteams U | 7 | 12 | 84 | Nelson Agholor | WR | NE |
| Doubleteams U | 8 | 1 | 85 | Donovan Peoples-Jones | WR | CLE |
| Hank | 8 | 2 | 86 | Velus Jones | WR | CHI |
| Don't Sleep on the Streets | 8 | 3 | 87 | Jason Sanders | PK | MIA |
| Night Owls SF BB F77 | 8 | 4 | 88 | WAS Team Defense | DF | WAS |
| Depot | 8 | 5 | 89 | KJ Hamler | WR | DEN |
| DSS SF BB #129 | 8 | 6 | 90 | Calvin Austin | WR | PIT |
| Inglourious Basterds | 8 | 7 | 91 | Mark Ingram | RB | NO |
| Show Me Your TDs | 8 | 8 | 92 | Mason Crosby | PK | GB |
| Tweety Birds | 8 | 9 | 93 | James Washington | WR | DAL |
| Mad Genius of FB 77SFBBD129 | 8 | 10 | 94 | Phillip Walker | QB | CAR |
| Mahomes Golden Tanks | 8 | 11 | 95 | Tyler Badie | RB | BAL |
| Tweety Birds | 8 | 12 | 96 | Mo Alie-Cox | TE | IND |
| Doubleteams U | 9 | 1 | 97 | Dan Arnold | TE | JAC |
| Hank | 9 | 2 | 98 | O.J. Howard | TE | BUF |
| Don't Sleep on the Streets | 9 | 3 | 99 | Anthony Schwartz | WR | CLE |
| Night Owls SF BB F77 | 9 | 4 | 100 | Cole Beasley | WR | FA |
| Depot | 9 | 5 | 101 | PHI Team Defense | DF | PHI |
| DSS SF BB #129 | 9 | 6 | 102 | James White | RB | NE |
| Inglourious Basterds | 9 | 7 | 103 | Rodrigo Blankenship | PK | IND |
| Show Me Your TDs | 9 | 8 | 104 | Jamison Crowder | WR | BUF |
| Tweety Birds | 9 | 9 | 105 | Snoop Conner | RB | JAC |
| Mad Genius of FB 77SFBBD129 | 9 | 10 | 106 | Gardner Minshew | QB | PHI |
| Mahomes Golden Tanks | 9 | 11 | 107 | Kene Nwangwu | RB | MIN |
| Doubleteams U | 9 | 12 | 108 | Zack Moss | RB | BUF |
| Doubleteams U | 10 | 1 | 109 | Charlie Kolar | TE | BAL |
| Hank | 10 | 2 | 110 | Bryan Edwards | WR | LV |
| Don't Sleep on the Streets | 10 | 3 | 111 | Cole Turner | TE | WAS |
| Night Owls SF BB F77 | 10 | 4 | 112 | Parris Campbell | WR | IND |
| Depot | 10 | 5 | 113 | Matt Breida | RB | NYG |
| DSS SF BB #129 | 10 | 6 | 114 | Kendrick Bourne | WR | NE |
| Inglourious Basterds | 10 | 7 | 115 | Brandon Bolden | RB | LV |
| Show Me Your TDs | 10 | 8 | 116 | Taysom Hill | TE | NO |
| Tweety Birds | 10 | 9 | 117 | Ty Chandler | RB | MIN |
| Mad Genius of FB 77SFBBD129 | 10 | 10 | 118 | Sterling Shepard | WR | NYG |
| Mahomes Golden Tanks | 10 | 11 | 119 | Cade York | PK | CLE |
| Doubleteams U | 10 | 12 | 120 | Carson Strong | QB | PHI |
