| Team Name | Round | Pick | Overall | Player Name | Position | NFL Team |
| Perseverance | 1 | 1 | 1 | Breece Hall | RB | NYJ |
| Perseverance | 1 | 2 | 2 | Drake London | WR | ATL |
| Waltervision | 1 | 3 | 3 | Kenneth Walker | RB | SEA |
| Toronto Trash Pandas | 1 | 4 | 4 | Treylon Burks | WR | TEN |
| Kahler 500 #43 SF | 1 | 5 | 5 | Jameson Williams | WR | DET |
| Bobby Dazzler | 1 | 6 | 6 | Christian Watson | WR | GB |
| Rubicon 392 | 1 | 7 | 7 | Kenny Pickett | QB | PIT |
| Arge Boys SFJA | 1 | 8 | 8 | Garrett Wilson | WR | NYJ |
| Bobby Dazzler | 1 | 9 | 9 | James Cook | RB | BUF |
| Mustard Tiger | 1 | 10 | 10 | Chris Olave | WR | NO |
| Psychopaths | 1 | 11 | 11 | Skyy Moore | WR | KC |
| Coffee Is for Closers QB Dynasty | 1 | 12 | 12 | Malik Willis | QB | TEN |
| Perseverance | 2 | 1 | 13 | Jahan Dotson | WR | WAS |
| Perseverance | 2 | 2 | 14 | Isaiah Spiller | RB | LAC |
| Rubicon 392 | 2 | 3 | 15 | George Pickens | WR | PIT |
| Toronto Trash Pandas | 2 | 4 | 16 | Desmond Ridder | QB | ATL |
| Psychopaths | 2 | 5 | 17 | Matt Corral | QB | CAR |
| Bobby Dazzler | 2 | 6 | 18 | Rachaad White | RB | TB |
| Arge Boys SFJA | 2 | 7 | 19 | David Bell | WR | CLE |
| Arge Boys SFJA | 2 | 8 | 20 | Dameon Pierce | RB | HOU |
| Rubicon 392 | 2 | 9 | 21 | Zamir White | RB | LV |
| Romo's Revenge | 2 | 10 | 22 | Tyler Allgeier | RB | ATL |
| Psychopaths | 2 | 11 | 23 | Brian Robinson | RB | WAS |
| Toronto Trash Pandas | 2 | 12 | 24 | Marcus Mariota | QB | ATL |
| Bobby Dazzler | 3 | 1 | 25 | Sam Howell | QB | WAS |
| Coffee Is for Closers QB Dynasty | 3 | 2 | 26 | Trey McBride | TE | ARI |
| Kahler 500 #43 SF | 3 | 3 | 27 | John Metchie | WR | HOU |
| Coffee Is for Closers QB Dynasty | 3 | 4 | 28 | Alec Pierce | WR | IND |
| Toronto Trash Pandas | 3 | 5 | 29 | Odell Beckham | WR | FA |
| Bobby Dazzler | 3 | 6 | 30 | Jalen Tolbert | WR | DAL |
| Toronto Trash Pandas | 3 | 7 | 31 | Jarvis Landry | WR | FA |
| Arge Boys SFJA | 3 | 8 | 32 | Russell Gage | WR | TB |
| Arge Boys SFJA | 3 | 9 | 33 | Wan'Dale Robinson | WR | NYG |
| Toronto Trash Pandas | 3 | 10 | 34 | Marlon Mack | RB | HOU |
| Psychopaths | 3 | 11 | 35 | Tyler Higbee | TE | LAR |
| Toronto Trash Pandas | 3 | 12 | 36 | Robert Tonyan | TE | GB |
| Mustard Tiger | 4 | 1 | 37 | DeVante Parker | WR | NE |
| Romo's Revenge | 4 | 2 | 38 | Mecole Hardman | WR | KC |
| Toronto Trash Pandas | 4 | 3 | 39 | Hayden Hurst | TE | CIN |
| Waltervision | 4 | 4 | 40 | Tyrion Davis-Price | RB | SF |
| Waltervision | 4 | 5 | 41 | Tyler Badie | RB | BAL |
| Bobby Dazzler | 4 | 6 | 42 | Hassan Haskins | RB | TEN |
| DOC SF1 | 4 | 7 | 43 | Terrace Marshall | WR | CAR |
| Toronto Trash Pandas | 4 | 8 | 44 | Julio Jones | WR | FA |
| Kahler 500 #43 SF | 4 | 9 | 45 | Justyn Ross | WR | KC |
| Mustard Tiger | 4 | 10 | 46 | Jelani Woods | TE | IND |
| Psychopaths | 4 | 11 | 47 | Nyheim Hines | RB | IND |
| Romo's Revenge | 4 | 12 | 48 | Chris Carson | RB | SEA |
| Rubicon 392 | 5 | 1 | 49 | Greg Dulcich | TE | DEN |
| Toronto Trash Pandas | 5 | 2 | 50 | Keaontay Ingram | RB | ARI |
| Waltervision | 5 | 3 | 51 | Romeo Doubs | WR | GB |
| Coffee Is for Closers QB Dynasty | 5 | 4 | 52 | Kyren Williams | RB | LAR |
| Kahler 500 #43 SF | 5 | 5 | 53 | Brevin Jordan | TE | HOU |
| Perseverance | 5 | 6 | 54 | Jamaal Williams | RB | DET |
| DOC SF1 | 5 | 7 | 55 | Jamison Crowder | WR | BUF |
| Arge Boys SFJA | 5 | 8 | 56 | Isaih Pacheco | RB | KC |
| Rubicon 392 | 5 | 9 | 57 | K.J. Osborn | WR | MIN |
| Mustard Tiger | 5 | 10 | 58 | Pierre Strong | RB | NE |
| Psychopaths | 5 | 11 | 59 | Nico Collins | WR | HOU |
| Coffee Is for Closers QB Dynasty | 5 | 12 | 60 | LAR Team Defense | DF | LAR |
| Toronto Trash Pandas | 6 | 1 | 61 | Geno Smith | QB | SEA |
| Romo's Revenge | 6 | 2 | 62 | Jacoby Brissett | QB | CLE |
| Perseverance | 6 | 3 | 63 | Dareke Young | WR | SEA |
| Coffee Is for Closers QB Dynasty | 6 | 4 | 64 | William Fuller | WR | FA |
| Kahler 500 #43 SF | 6 | 5 | 65 | SF Team Defense | DF | SF |
| Bobby Dazzler | 6 | 6 | 66 | Calvin Austin | WR | PIT |
| DOC SF1 | 6 | 7 | 67 | Jonnu Smith | TE | NE |
| Arge Boys SFJA | 6 | 8 | 68 | D'Onta Foreman | RB | CAR |
| Rubicon 392 | 6 | 9 | 69 | Sammy Watkins | WR | GB |
| Mustard Tiger | 6 | 10 | 70 | LAC Team Defense | DF | LAC |
| Psychopaths | 6 | 11 | 71 | Khalil Shakir | WR | BUF |
| Toronto Trash Pandas | 6 | 12 | 72 | Velus Jones | WR | CHI |
| Waltervision | 7 | 1 | 73 | WAS Team Defense | DF | WAS |
| Romo's Revenge | 7 | 2 | 74 | Robbie Anderson | WR | CAR |
| Waltervision | 7 | 3 | 75 | Ty Chandler | RB | MIN |
| Coffee Is for Closers QB Dynasty | 7 | 4 | 76 | Samori Toure | WR | GB |
| Toronto Trash Pandas | 7 | 5 | 77 | Sony Michel | RB | MIA |
| Bobby Dazzler | 7 | 6 | 78 | Isaiah Likely | TE | BAL |
| DOC SF1 | 7 | 7 | 79 | Tyler Huntley | QB | BAL |
| Arge Boys SFJA | 7 | 8 | 80 | Jerome Ford | RB | CLE |
| Rubicon 392 | 7 | 9 | 81 | Curtis Samuel | WR | WAS |
| Mustard Tiger | 7 | 10 | 82 | Chuba Hubbard | RB | CAR |
| Psychopaths | 7 | 11 | 83 | Abram Smith | RB | NO |
| Toronto Trash Pandas | 7 | 12 | 84 | Darrel Williams | RB | KC |
